As a leading supplier for reagents in the biotechnology field, Creative BioMart understand the importance of convenient and easy-to-use systems for high level expression and sample purification. With the commitment to provide advanced tools for protein expression and purification, Creative BioMart recently updated its Bacterial Expression Systems (E. coli / Bacillus).
Due to its nature, the bacterial expression system is an ideal protein expression system. It is usually the first choice for the production of recombinant proteins and antibodies. So far, many bacteria have been well studied.
Among a large number of bacteria, E. coli and Bacillus subtilis cell lines are the most commonly used recombinant protein expression hosts. They are quickly copied at very low cost under suitable conditions, and the expression level is high. This feature makes them an effective and economical way of mass production. Their genome has been completely sequenced, and their genetic background and metabolic pathways are well known. In addition, because of its simple structure, bacteria are easier to transfect than eukaryotes. These desired characteristics make the expression process easier and faster.
Bacterial expression systems have proven to be the first choice for initial development in laboratory studies and commercial production compared to various other expression systems. The advantages of bacterial expression include thorough grinding of the system, low cost, high expression yield, easy scale-up and short turnaround time.
Creative BioMart’s E.coli expression platform collects a variety of expression vectors with different N and C terminal tags as well as different host strains to ensure the selection of the most efficient system. For insoluble proteins, experienced PhD-level scientists at Creative BioMart have developed an efficient protein refolding system consisting of optimized refolding buffers and procedures. As for fermentation scale, Creative BioMart provides bioreactors of 5 to 20,000 liters to meet all its customers’ needs.
Moreover, Creative BioMart's Bacillus subtilis system is ideal for products expressing monomeric proteins at high expression levels, and in combination with its proprietary fermentation protocol, the process can be rapidly developed and scaled up to support early clinical testing.
“Featured as simple, well-understood genetics, easy to manipulate, fast expression with short doubling time, easy to purify from inclusion bodies, minimal culturing cost, bacterial expression systems at Creative BioMart are surely to meet your specific needs.” Commented Linna, the chief marketing staff at Creative BioMart.
Besides bacterial expression systems, Creative BioMart offers a wide range of protein expression systems including Nicotiana tabacum specific expression platform, Rice endosperm specific expression platform, Baculovirus-Insect cell expression systems (SF9, SF21, S2, T.ni / HI-5), Cell-Free in Vitro protein expression, Mammalian expression Systems (CHO / HEK293), Yeast expression Systems (P pastoris / S cerevisiae), High-throughput protein production, etc. Visit https://www.creativebiomart.net/Protein-expression-Services.htm to view the whole list.
About Creative BioMart
Starting from a small supplier of proteins and enzymes for academic institutes and biotech companies, Creative BioMart has always been focusing on developing high quality protein products like recombinant proteins, native proteins, GMP proteins, etc. and efficient protein manufacturing services including protein expression, protein labeling, protein interaction etc.