BOC Sciences has grown to be the most potent pseudoUridine manufacturer, with the annual production of pseudoUridines and N1-MethylpseudoUridines exceeding 500 kg and 1000 kg respectively. The amazing numbers are strong evidence of its strong production capacity, which, however, cannot be concluded as all its skills and strengths. BOC Sciences' capabilities are also displayed in other aspects, particularly in the comprehensive catalog of phosphoramidites, pseudoUridines and their derivatives.
It's worth noting that massive pseudoUridines of BOC Sciences have been delivered to global partners for their mRNA-related research in the fields of cancer immunotherapy and other biomedical therapies. Researchers specializing in the above areas were previously perplexed by the problem of mRNA immune toxicity in the host, which limited the application of mRNAs in drugs and vaccines. Thanks to the ground-breaking finding that mRNA modifications by utilizing naturally occurring modified nucleotides such as pseudoUridine-5'-triphosphate or chemically synthesized pseudoUridines can solve the problem to a large extent.
BOC Sciences, equipped with advanced facilities, a group of dedicated experts, and most importantly the far-sighted leadership, has thrown itself into the production of pseudoUridines and related derivatives for years. The most valuable is its promise of products with high-level purity which will definitely meet industry guidelines or can be even beyond what researchers expect.
N1-Methyl-2'-O-MethylpseudoUridine-5'-Triphosphate typically represents BOC Sciences' ability to guarantee high-purity production. The modified NTP for incorporation into mRNAs using T7 RNA polymerase can decrease the immunogenicity of the resulting mRNA. BOC Sciences commits to keeping its purity level always over 95%, a sufficient condition to fit both needs of research and industrial use.
"Everyone involved in the pharma industry is aware of the important roles of highly-purified raw materials. However, it is a demanding work that requires versatile skills so that many of our peers are still struggling for it," a technical advisor of BOC Sciences said.
To learn more about the established (bio)chemical manufacturer based in the United States, researchers, procurement managers, or anyone interested are encouraged to attend the end-to-end exhibitions CPhI North America and TIDES USA 2022. BOC Sciences' booth numbers are 1319 and 233 respectively. Or the simplest way is to visit https://nucleotech.bocsci.com/.
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BOC Sciences is a respectable (bio)chemical raw material supplier with decades of experience serving the pharmaceutical industry. It's now the largest supplier of pseudoUridines all over the world and is a solid supporter of the pressing production of COVID-19 mRNA vaccines.