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Diagnostics World | Researchers in Israel recently showcased a novel platform that can be used in the future for the early diagnosis of Parkinson’s disease (PD) by quantifying the distribution of alpha-synuclein (α-syn) in skin biopsies. A proof-of-concept study in humans, supported in part by the Michael J. Fox Foundation, suggests the single-molecule-level detection method might enable the disease to be detected up to 20 years before the first motor symptoms appear.
Nov 13, 2024
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Diagnostics World | Recent years have seen progress toward developing tools that are designed to analyze a human breath sample to detect, diagnose, or monitor various health issues. Some of these efforts have focused on combating deadly infectious diseases, with intentions of creating cost-effective, easy-to-use breathalyzers capable of being deployed in rural, remote, and low-resource settings.
Nov 12, 2024
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Diagnostics World | A next-generation liquid biopsy approach combining cell-free DNA (cfDNA) “fragmentome” and protein biomarker analyses could aid in the early detection of ovarian cancer, suggests a recent study by researchers in the U.S., The Netherlands, and Denmark. The DELFI-Pro classifier was found to have a high positive predictive value, a key accuracy metric.
Nov 7, 2024
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Diagnostics World | A diagnostic test invented at the University of Arizona has demonstrated its potential to predict the likelihood of relapse or recurrence among patients with early-stage breast cancer and their response to antifibrotic therapy. The tool, known as MeCo Score, measures metastatic risk based on the acclimation of cancer cells to the mechanical stiffness of tissue (fibrosis) as computed from RNA sequencing data on tumor samples.
Nov 4, 2024
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Diagnostics World | In another few years, low-density lipoprotein (LDL) and high-density lipoprotein (HDL) analytes may be “obsolete” because the famously bad and good guys in standard cholesterol tests provide less useful information about heart health than other lipid molecules circulating in the blood. The evidence emerges from a recent study in children and adolescents with overweight or obesity finding a new relationship between lipids and diseases impacting metabolism.
Oct 31, 2024
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Diagnostics World | Revvity launches the in vitro diagnostic EURORealTime APOE assay in European countries that accept the CE mark; Withings Health Solutions announces a first-of-its-kind cellular blood pressure monitor; and more.
Oct 30, 2024
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Diagnostics World | Cytovale plans to commercially expand IntelliSep, the company’s sepsis diagnostic test, to more hospital emergency departments and health systems nationwide; C2N Diagnostics will continue to develop their next-generation tests specific to tau tangle pathology; and more.
Oct 29, 2024